Basic product information
Phenacetin；White powder；It is a medical intermediate
Country of origin：CHINA
Nature:White glossy scaly crystals or white crystalline powder. Melting point 137-138℃, refraction 1.571. Insoluble in water, slightly soluble in ether, slightly soluble in boiling water, soluble in ethanol and chloroform. Dissolves in concentrated sulfuric acid does not show color, to the solution after dropping nitric acid is orange yellow. Odorless, slightly bitter taste.
Function:The antipyretic effect of phenacetin is stronger than the analgesic effect. The action intensity is similar to aspirin, the action is slow and lasting, and the toxicity is low. The results showed that the product and its metabolite paracetamol had antipyretic effect. When phenacetin and enzyme inhibitors cannot be converted to paracetamol, it has a significant antipyretic effect. Therefore, the antipyretic effect of the drug is not only caused by its active product, paracetamol.
|Melting point||133-136 °C (lit.)|
|Storage||Sealed in dry,Room Temperature|
The antipyretic and analgesic effect of phenacetin is similar to that of acetylsalicylic acid. It is mainly used as antipyretic and analgesic drug with slow and lasting effect. It has good efficacy in the treatment of headache, neuralgia, arthralgia and fever, but has weak anti-rheumatism and anti-inflammatory effect. Excessive dose can lead to methemoglobin disease, resulting in hypoxia, long-term medication can damage the kidney, and even cause nipple necrosis, should be used with caution. Due to its toxic side effects and the rapid development of other similar drugs, the drug Chemicalbook has been discontinued in isolation and is only used as a bulk drug and other drugs in combination preparations. It is often combined with aspirin and caffeine to form compound aspirin, which consists of phenacetin 0.162g, aspirin 0.227g and caffeine 0.035g. It is less toxic and used to treat colds and colds. If a small amount of puermin is added to the above drugs, it can also be made into puermin cold tablets, which can be used to treat cold, headache, neuralgia, rheumatic pain, etc.